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sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Calculated MW | 11kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human DEFB132 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | DEFB32; UNQ827 |
∫-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, ∫-defensins are developmentally regulated. The family of ∫-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many ∫-defensins also are involved in sperm maturation and capacitation. ∫-defensin 32, also known as ∫-defensin 132, is a 95 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active.
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