|Reactivity||Human Mouse Rat|
|Tested applications||WB ICC IF IP|
|Recommended Dilution||WB 1:500 - 1:2000
ICC 1:50 - 1:200
IF 1:50 - 1:100
IP 1:20 - 1:50|
|Calculated MW||100 kDa|
|Observed MW||Refer to figures|
|Immunogen||Recombinant protein of human DGCR8|
|Storage Buffer||Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Synonym||Gy1; pasha; DGCRK6; C22orf12;|
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
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