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+1-888.733.6849
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| Reactivity | Human Mouse Rat |
| Tested applications | WB ICC IF IP |
| Recommended Dilution | WB 1:500 - 1:2000 ICC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:20 - 1:50 |
| Calculated MW | 100 kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human DGCR8 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | Gy1; pasha; DGCRK6; C22orf12; |
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
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