DLC1-Polyclonal Antibodies

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DLC1

Qty


Total
$220
Catalog #
A1921
Antibody Type
Polyclonal Antibody
Gene ID
10395
Swiss Prot
Q96QB1
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200
Calculated MW171kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human DLC1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymHP; ARHGAP7; STARD12; p122-RhoGAP;
Images
  • A1921: image 1

    Western blot analysis of extracts of mouse lung cell lines, using DLC1 antibody.

  • A1921: image 2

    Immunohistochemistry of paraffin-embedded rat kidney using DLC1 antibody at dilution of 1:200 (400x lens).

Background

This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.

Protocol

N/A

MSDS
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