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| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IF IP |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:20 - 1:200 IF 1:20 - 1:100 IP 1:20 - 1:50 |
| Calculated MW | 62kDa |
| Observed MW | Refer to figures |
| Immunogen | A synthetic Peptide of human DPYSL2 |
| Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
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