|Reactivity||Human Mouse Rat|
|Tested applications||WB IHC IF IP|
|Recommended Dilution||WB 1:500 - 1:2000
IHC 1:20 - 1:200
IF 1:20 - 1:100
IP 1:20 - 1:50|
|Observed MW||Refer to figures|
|Immunogen||A synthetic Peptide of human DPYSL2|
|Storage Buffer||Store at 4℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
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