E2F1-Polyclonal Antibodies

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E2F1

Qty


Total
$220
Catalog #
A0051
Antibody Type
Polyclonal Antibody
Gene ID
1869
Swiss Prot
Q01094
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:1000
Calculated MW47kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human E2F1
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationbk
SynonymE2F-1;RBAP1;RBBP3;RBP3;
Images
  • A0051: image 1

    Western blot analysis of extracts of HeLa cell line, using E2F1 antibody.

Background

DNA tumor viruses appear to have transforming activity due to their binding and inactivating to the RB1 gene products, and transcription facotr E2F, which is first identified as a DNA-binding protein essential for E1A-dependent activation of the advenovirus E2 promoter. The complex DRTF1/E2F involves in the control of cell-cycle progression from G1 to S phase. E2F1, one of E2F preferentially binds to RB1 protein in a cell-cycle dependent manner. It mediates both cell proliferation and p53-dependent apoptosis.

Protocol

N/A

MSDS
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