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Reactivity | Human |
Tested applications | WB |
Recommended Dilution | WB 1:200 - 1:1000 |
Calculated MW | 49kDa |
Observed MW | Refer to figures |
Immunogen | A synthetic peptide of human EDNRA |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | ETA; ET-A; ETAR; ETRA; MFDA; ETA-R; hET-AR; |
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
N/A