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| Reactivity | Human Mouse |
| Tested applications | WB FC |
| Recommended Dilution | WB 1:200 - 1:2000 FC 1:20 - 1:50 |
| Calculated MW | 20kDa |
| Observed MW | Refer to figures |
| Immunogen | A synthetic peptide of human EEF1E1 |
| Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | b |
| Synonym | P18; AIMP3; |
This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.
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