EHMT1-Phosphorylated Antibodies

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EHMT1

Qty


Total
$220
Catalog #
A8513
Antibody Type
Polyclonal Antibody
Gene ID
79813
Swiss Prot
Q9H9B1
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:2000
Calculated MW141kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human EHMT1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymGLP; GLP1; KMT1D; FP13812; EUHMTASE1; Eu-HMTase1; bA188C12.1;
Images
  • A8513: image 1

    Western blot analysis of extracts of various cells, using EHMT1 antibody.

Background

The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants.

Protocol

N/A

MSDS
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