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Reactivity | Human Mouse Rat |
Tested applications | WB |
Recommended Dilution | WB 1:1000 - 1:2000 |
Calculated MW | 50kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human EIF2B3 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | EIF-2B; EIF2Bgamma; |
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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