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Reactivity | Human Mouse Rat |
Tested applications | WB |
Recommended Dilution | WB 1:200 - 1:2000 |
Calculated MW | 48kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human ETF1 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | j |
Synonym | ERF; RF1; ERF1; TB3-1; D5S1995; SUP45L1; |
This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.
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