FBL-Polyclonal Antibodies

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FBL

Qty


Total
$220
Catalog #
A0158
Antibody Type
Polyclonal Antibody
Gene ID
2091
Swiss Prot
P22087
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:1000
Calculated MW34kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human FBL
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationj
SynonymFBL;FIB;FLRN;RNU3IP1
Background

FBL is a 2'-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place (1,2). FBL associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2'-O-ribose methylation of targeted nucleotides within the rRNA sequence (3,4). The sequence, structure and function of FBL are highly conserved and FBL gene expression is essential for early embryonic development (5).

Protocol

N/A

MSDS
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