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Reactivity | Human Mouse Rat |
Tested applications | WB IF |
Recommended Dilution | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
Calculated MW | 45kDa |
Observed MW | Refer to Figures |
Immunogen | A synthetic peptide of human FCGR3A |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | CD16; FCG3; CD16A; FCGR3; IGFR3; FCR-10; FCRIII; FCGRIII; FCRIIIA; |
CD16a is involved in the removal of antigen-antibody complexes from the circulation, as well as other antibody-dependent responses. The receptor encoded by CD16a is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide. Mutations in CD16a have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia (1).
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