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Reactivity | Human |
Tested applications | WB FC |
Recommended Dilution | WB 1:500 - 1:1000 FC 1:20 - 1:50 |
Calculated MW | 36kDa |
Observed MW | Refer to Figures |
Immunogen | A synthetic peptide of human FOSB |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | k |
Synonym | AP-1; G0S3; GOS3; GOSB |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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