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Reactivity | Human |
Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
Calculated MW | 58kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human FTO |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | FTO; |
The exact function of FTO is not known. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Studies of type 2 diabetes indicate FTO is related to diabetes susceptibility. Mutation in this protein has been associated with growth retardation, developmental delay, coarse facies, and early death (1).
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