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sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IF |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Calculated MW | 48kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human GATM |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | AT; AGAT; CCDS3; |
Western blot analysis of extracts of various cell lines, using GATM antibody.
Immunohistochemistry of paraffin-embedded liver cancer using GATM antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Mouse kidney using GATM antibody at dilution of 1:100 (x400 lens).
Immunofluorescence analysis of A549 cell using GATM antibody. Blue: DAPI for nuclear staining.
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
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