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| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Calculated MW | 38kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human HNRNPD |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | j |
| Synonym | P37; AUF1; AUF1A; HNRPD; hnRNPD0; |
Western blot analysis of extracts of various cell lines, using HNRNPD antibody.
Immunohistochemistry of paraffin-embedded Human adenoma of uterine muscle using HNRNPD antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Human adenomyosis using HNRNPD antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Human gastric using HNRNPD antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Human gastric cancer using HNRNPD antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Human liver injury using HNRNPD antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Mouse brain using HNRNPD antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Mouse liver using HNRNPD antibody at dilution of 1:100 (x400 lens).
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
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