HSPA9-Polyclonal Antibodies

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HSPA9

Qty


Total
$220
Catalog #
A0055
Antibody Type
Polyclonal Antibody
Gene ID
3313
Swiss Prot
P38646
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB
Recommended DilutionWB 1:1000 - 1:2000
Calculated MW74kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human HSPA9
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationbhj
SynonymHSPA9;CSA;GRP75;HSPA9B;MGC4500;MOT;MOT2;MTHSP75;PBP74;mot-2
Background

Grp75, also known as mortalin, is a member of Hsp70 family of chaperone proteins that is not heat-inducible (1,2). This protein is essential for transporting many mitochondrial proteins from the cytoplasm to mitochondria (3). Grp75 inactivates the tumor suppressor p53 (4). Studies found that Grp75 is overexpressed in many tumor tissues and immortalized human cell lines, suggesting its role in the tumor formation (5). Grp75 is also implicated in cell aging, as its overexpression appears to prolong the life span of human fibroblasts (6).

Protocol

N/A

MSDS
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