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Reactivity | Human Mouse Rat |
Tested applications | WB IHC |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Calculated MW | 60 kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human HSPD1 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | HLD4; CPN60; GROEL; HSP60; HSP65; SPG13; HSP-60; HuCHA60; |
Immunohistochemistry of paraffin-embedded mouse skin using HSPD1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human lung using HSPD1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human kidney using HSPD1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using HSPD1 antibody at dilution of 1:100 (40x lens).
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
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