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Reactivity | Human |
Tested applications | WB IHC ICC |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:500 - 1:1000 ICC 1:500 - 1:1000 |
Calculated MW | 20kDa |
Observed MW | Refer to Figures |
Immunogen | A synthetic Peptide of human IGF2 |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | IGF-II; PP9974; C11orf43; |
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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