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+1-888.733.6849
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| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Calculated MW | 64kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human IGF2BP3 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | j |
| Synonym | KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3; |
Western blot analysis of extract of various cells, using IGF2BP3 antibody.
Immunohistochemistry of paraffin-embedded rat heart using IGF2BP3 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver using IGF2BP3 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach cancer using IGF2BP3 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using IGF2BP3 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using IGF2BP3 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using IGF2BP3 antibody at dilution of 1:100 (40x lens).
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
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