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Reactivity | Mouse Rat |
Tested applications | WB |
Recommended Dilution | WB 1:500 - 1:2000 |
Calculated MW | 41kDa |
Observed MW | Refer to Figures |
Immunogen | A synthetic peptide of human IL12B |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | CLMF; NKSF; CLMF2; NKSF2; IL-12B; |
IL-12 beta is a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Overexpression of this protein was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of IL-12 has been reported to be associated with the severity of atopic and non-atopic asthma in children (1).
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