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Reactivity | Human Mouse Rat |
Tested applications | WB IHC |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
Calculated MW | 20kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human IL25 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | IL17E; |
Western blot analysis of extract of various cells, using IL25 antibody.
Immunohistochemistry of paraffin-embedded rat lung using IL25 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate using IL25 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse lung using IL25 antibody at dilution of 1:100 (40x lens).
The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.
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