IL27-Polyclonal Antibodies

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IL27

Qty


Total
$220
Catalog #
A5498
Antibody Type
Polyclonal Antibody
Gene ID
246778
Swiss Prot
Q8NEV9
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200
Calculated MW27kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human IL27
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonymp28; IL30; IL-27; IL27A; IL-27A; IL27p28;
Images
  • A5498: image 1

    Western blot analysis of extracts of various cell lines, using IL27 antibody.

  • A5498: image 2

    Immunohistochemistry of paraffin-embedded human colon using IL27 antibody at dilution of 1:200 (x400 lens)

Background

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Protocol

N/A

MSDS
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