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Reactivity | Human Mouse Rat |
Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Calculated MW | 100kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human INTS6 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | HDB; INT6; DBI-1; DDX26; DICE1; DDX26A; Notchl2; |
Western blot analysis of extracts of various cell lines, using INTS6 antibody.
Immunohistochemistry of paraffin-embedded Human mammary cancer using INTS6 antibody at dilution of 1:100 (x400 lens).
Immunohistochemistry of paraffin-embedded Mouse lung using INTS6 antibody at dilution of 1:100 (x400 lens).
Immunofluorescence analysis of A549 cell using INTS6 antibody. Blue: DAPI for nuclear staining.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.
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