INVS-Monoclonal Antibodies

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INVS

Qty


Total
$220
Catalog #
A10298
Antibody Type
Polyclonal Antibody
Gene ID
27130
Swiss Prot
Q9Y283
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:2000
Calculated MW118kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human INVS
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymINV; NPH2; NPHP2;
Images
  • A10298: image 1

    Western blot analysis of extract of various cells, using INVS antibody.

Background

This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Protocol

N/A

MSDS
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