KDR-Methylated Antibodies

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KDR

Qty


Total
$300
Catalog #
A1484
Antibody Type
Monoclonal Antibody
Gene ID
3791
Swiss Prot
P35968
Size
Species
Mouse
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC IF IP
Recommended DilutionWB 1:500 - 1:1000 IHC 1:50 - 1:500 IF 1:50- 1:500 IP 1:20- 1:100
Calculated MW152kDa
Observed MWRefer to Figures
ImmunogenRecombinant Protein of human KDR
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationa
SynonymFLK1; CD309; VEGFR; VEGFR2
Images
  • A1484: image 1

    Western blot analysis of mouse liver cell lysate using KDR antibody.

Background

KDR has also been designated as VEFR-2 (Vascular endothelial growth factor receptor 2), CD309 (cluster of differentiation 309) and Flk1 (fetal liver kinase 1). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. KDR is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Protocol

N/A

MSDS
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