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Reactivity | Human Mouse |
Tested applications | WB IHC IF |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
Calculated MW | 30kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human KLK10 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | NES1; PRSSL1; |
Western blot analysis of extracts of various cells, using KLK10 antibody.
Immunohistochemistry of paraffin-embedded human liver cancer using KLK10 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate using KLK10 antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of A549 cell using KLK10 antibody. Blue: DAPI for nuclear staining.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
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