LRAT-Polyclonal Antibodies

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LRAT

Qty


Total
$220
Catalog #
A6647
Antibody Type
Polyclonal Antibody
Gene ID
9227
Swiss Prot
O95237
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Rat
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Calculated MW25kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human LRAT
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymLCA14;
Images
  • A6647: image 1

    Immunofluorescence analysis of U2OS cell using LRAT antibody. Blue: DAPI for nuclear staining.

Background

The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.

Protocol

N/A

MSDS
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