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+1-888.733.6849
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| Reactivity | Human |
| Tested applications | WB IHC |
| Recommended Dilution | WB 1:200 - 1:2000 IHC 1:50 - 1:200 |
| Calculated MW | 15kDa |
| Observed MW | Refer to Figures |
| Immunogen | A synthetic peptide of human LSM1 |
| Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | j |
| Synonym | CASM; YJL124C; |
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
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