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Reactivity | Human Mouse |
Tested applications | WB IHC |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Calculated MW | 31kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human M6PR |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | SMPR; MPR46; CD-MPR; MPR 46; MPR-46; |
Western blot analysis of extracts of Mouse kidney cell line, using M6PR antibody.
Immunohistochemistry of paraffin-embedded human liver injury using M6PR antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human gastric using M6PR antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded mouse heart using M6PR antibody at dilution of 1:100 (x40 lens).
This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.
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