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Reactivity | Human Mouse Rat |
Tested applications | WB ICC IF IP FC |
Recommended Dilution | WB 1:500 - 1:2000 ICC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:20 - 1:50 FC 1:20 - 1:50 |
Calculated MW | 42/44 kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human MAPK3 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
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