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+1-888.733.6849
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| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC ICC IF IP FC |
| Recommended Dilution | WB 1:500 - 1:1000 IHC 1:50 - 1:200 ICC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:20 - 1:50 FC 1:20 - 1:50 |
| Calculated MW | 37/29 kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human MCL1 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; |
Immunohistochemistry of paraffin-embedded human pancreas using MCL1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human breast using MCL1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human kidney using MCL1 antibody at dilution of 1:100 (40x lens).
Immunofluorescence
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
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