MMP2-Monoclonal Antibodies

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MMP2

Qty


Total
$220
Catalog #
A0317
Antibody Type
Polyclonal Antibody
Gene ID
4313
Swiss Prot
P08253
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsIHC
Recommended DilutionIHC 1:50 - 1:100
Calculated MW72kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human MMP2
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymMMP2;CLG4;CLG4A;MMP-II;MONA;TBE-1 ;
Background

The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors and adhesion molecules (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (5).

Protocol

N/A

MSDS
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