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Reactivity | Human Mouse Rat |
Tested applications | WB IHC IP |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:20 - 1:200 IP 1:20 - 1:50 |
Calculated MW | 66kDa |
Observed MW | Refer to figures |
Immunogen | A synthetic Peptide of human MPP7 |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are involved in multimerization of MAGUKs. MPP7 belongs to the p55 stardust subfamily of MAGUKs, which is named for a Drosophila gene required for establishment of cell polarity in the developing fly embryo (Bohl et al., 2007
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