MX1-Polyclonal Antibodies

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MX1

Qty


Total
$220
Catalog #
A1780
Antibody Type
Polyclonal Antibody
Gene ID
4599
Swiss Prot
P20591
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200
Calculated MW76kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human MX1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationb
SynonymMX; MxA; IFI78; IFI-78K;
Images
  • A1780: image 1

    Western blot analysis of extracts of mouse spleen tissue, using MX1 antibody.

Background

Mx1 (also known as MxA) is a GTPase that belongs to the Mx family of proteins, which are ubiquitous in eukaryotes and involved in the immune response to viral infections. The human Mx1 is localized in the cytoplasm interfering with the translation of viral proteins, whereas the mouse Mx1 accumulates in the nucleus and inhibits the primary transcription of viral RNA. Mx1 expression is induced by treatment with α/β interferon (INF). This antibody can recognize the endogenous Mx1 protein in several tissues like lung and spleen.

Protocol

N/A

MSDS
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