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+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-617.299.7367 (Int’l)
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sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IF |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Calculated MW | 18kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human NCBP2 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | CBC2; NIP1; CBP20; PIG55; |
Western blot analysis of extracts of various cells, using NCBP2 antibody.
Immunohistochemistry of paraffin-embedded human colon using NCBP2 antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate using NCBP2 antibody at dilution of 1:200 (40x lens).
Immunofluorescence analysis of MCF7 cell using NCBP2 antibody. Blue: DAPI for nuclear staining.
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.
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