NCOR1-Polyclonal Antibodies

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NCOR1

Qty


Total
$220
Catalog #
A7046
Antibody Type
Polyclonal Antibody
Gene ID
9611
Swiss Prot
O75376
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Calculated MW270kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human NCOR1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymN-CoR; TRAC1; N-CoR1; hN-CoR; PPP1R109;
Images
  • A7046: image 1

    Western blot analysis of extracts of various cells, using NCOR1 antibody.

  • A7046: image 2

    Immunofluorescence analysis of U20S cell using NCOR1 antibody. Blue: DAPI for nuclear staining.

Background

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

Protocol

N/A

MSDS
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