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sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IF |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:100 |
| Calculated MW | 21kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human NCR3 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | 1C7; MALS; CD337; LY117; NKp30; |
Immunohistochemistry of paraffin-embedded mouse lung using NCR3 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded rat lung using NCR3 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human esophagus using NCR3 antibody at dilution of 1:100 (x40 lens).
Immunofluorescence analysis of U2OS cell using NCR3 antibody. Blue: DAPI for nuclear staining.
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
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