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Reactivity | Human Mouse |
Tested applications | WB IHC |
Recommended Dilution | WB 1:500 - 1:1000 IHC 1:50 - 1:100 |
Calculated MW | 23kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human NEUROG3 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | k |
Synonym | ngn3; Atoh5; NGN-3; Math4B; bHLHa7; |
Neurogenin-3 is a protein that in humans is encoded by the NEUROG3 gene. Neurogenin-3 is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine. It belongs to a family of basic helix-loop-helix (bHLH) transcription factors involved in the determination of neural precursor cells in the neuroectoderm. The pancreas and brain the major splicing isoform does not code for a protein. Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1.
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