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sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Calculated MW | 28kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human NFU1 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | Nfu; NifU; HIRIP; MMDS1; NIFUC; CGI-33; HIRIP5; |
Western blot analysis of extracts of various cell lines, using NFU1 antibody.
Immunohistochemistry of paraffin-embedded rat lung using NFU1 antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded human colon using NFU1 antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using NFU1 antibody at dilution of 1:200 (40x lens).
This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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