NOS1-Methylated Antibodies

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NOS1

Qty


Total
$220
Catalog #
A1485
Antibody Type
Polyclonal Antibody
Gene ID
4842
Swiss Prot
P29475
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC IP
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IP 1:20 - 1:50
Calculated MW160kDa
Observed MWRefer to Figures
ImmunogenRecombinant Protein of human NOS1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationiq
SynonymNOS1;IHPS1;N-NOS;NC-NOS;NOS;Bnos;nNOS
Images
  • A1485: image 1

    Western blot analysis of extracts of mouse brain cell line, using NOS1 antibody.

Background

Nitric Oxide Synthase (NOS) catalyses the formation of nitric oxide (NO) and citruline from L-arginine, oxygen and cofactors. Three family members have been characterized: neuronal NOS (nNOS), which is found primarily in neuronal tissue; inducible NOS (iNOS), which is induced by interferon gamma and lipopolysaccharides in the kidney and cardiovascular system; and endothelial NOS (eNOS), which is expressed in blood vessels (1). NO is a messenger molecule with diverse functions throughout the body including the maintenance of vascular integrity, homeostasis, synaptic plasticity, long-term potentiation, learning, and memory (2,3).nNOS binds selectively to the second PDZ domain of PSD-95, and the enzymatic activity of nNOS is either downregulated by phosphorylation at Ser847 by CaM-KII or stimulated by calcium influxes governed by the NMDA receptor channels (4-5).

Protocol

N/A

MSDS
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