NQO1-Polyclonal Antibodies

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NQO1

Qty


Total
$220
Catalog #
A0047
Antibody Type
Polyclonal Antibody
Gene ID
1728
Swiss Prot
P15559
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC IF FC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 FC 1:20 - 1:50
Calculated MW31kDa
Observed MWRefer to Figures
ImmunogenRecombinant Protein of human NQO1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationj
SynonymDTD; QR1; DHQU; DIA4; NMOR1; NMORI;
Images
  • A0047: image 1

    Western blot analysis of extracts of K562 cell line, using NQO1 antibody.

Background

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Protocol

N/A

MSDS
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