NRAS-Polyclonal Antibodies

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NRAS

Qty


Total
$220
Catalog #
A0155
Antibody Type
Polyclonal Antibody
Gene ID
4893
Swiss Prot
P01111
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB IHC FC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:100 FC1:20 - 1:50
Calculated MW21kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human NRAS
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymALPS4;N-ras;NRAS1;NS6;GTPase NRas antibody;Transforming protein N-Ras antibody;
Images
  • A0155: image 1

    Western blot analysis of extracts of C6 cell line, using NRAS antibody.

Background

Ras (p21), a signal transducer, was first characterized as the transforming genes of Harvey & Kristen sarcoma virus. The Ras family (H-Ras, N-Ras, and K-Ras) regulates cell growth, differentiation and apoptosis. Switching from an active or resting state, Ras can either bind GTP or GDP respectively. In the triphosphate conformation, Ras will interact with GTPase activating protein (GAP) to increase its activit. Mutations in any of the three isoforms can convert these proteins into active oncogenes. Additionally, Ras mutations are found in 30 % of all human cancer.

Protocol

N/A

MSDS
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