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Reactivity | Human Mouse |
Tested applications | WB IHC |
Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Calculated MW | 31kDa |
Observed MW | Refer to Figures |
Immunogen | Recombinant protein of human OLR1 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | LOX1; LOXIN; SLOX1; CLEC8A; SCARE1; |
Western blot analysis of extracts of various cell lines, using OLR1 antibody.
Immunohistochemistry of paraffin-embedded human stomach cancer using OLR1 antibody at dilution of 1:200 (x400 lens).
Immunohistochemistry of paraffin-embedded human stomach using OLR1 antibody at dilution of 1:200 (x400 lens).
Immunohistochemistry of paraffin-embedded mouse testis using OLR1 antibody at dilution of 1:200 (x400 lens).
Immunohistochemistry of paraffin-embedded Human kidney using OLR1 antibody at dilution of 1:100 (x400 lens).
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
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