P4HTM-Polyclonal Antibodies

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P4HTM

Qty


Total
$220
Catalog #
A6143
Antibody Type
Polyclonal Antibody
Gene ID
54681
Swiss Prot
Q9NXG6
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:100
Calculated MW56kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human P4HTM
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymPH4; PH-4; PHD4; EGLN4; HIFPH4; P4H-TM;
Images
  • A6143: image 1

    Western blot analysis of extracts of various cell lines, using P4HTM antibody.

  • A6143: image 2

    Immunofluorescence analysis of HeLa cell using P4HTM antibody. Blue: DAPI for nuclear staining.

Background

The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified.

Protocol

N/A

MSDS
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