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Reactivity | Human Mouse Rat |
Tested applications | WB IHC |
Recommended Dilution | WB 1:200 - 1:500 IHC 1:50 - 1:100 |
Calculated MW | 51kDa |
Observed MW | Refer to Figures |
Immunogen | A synthetic peptide of human PACSIN1 |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | KIAA1379; SDPI; |
PACSINs are members of a family of cytoplasmic adapter proteins, which share a conserved C-terminal protein binding SH3 domain and a CDC15-NT domain. PACSIN 1-related proteins include syndapin 1 (the rat homolog of PACSIN 1), FAP52, EM13, and PSTPIP, all of which seem to be involved in signaling pathways associated with cytoskeletal organization. PACSIN 1 expression is restricted to terminally differentiated neural tissue, whereas PACSIN 2 is widely expressed. PACSIN 2 shows vesicle-like distribution and may be involved in regulating endocytotic processes .
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