PCBP1-Monoclonal Antibodies

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PCBP1

Qty


Total
$220
Catalog #
A1044
Antibody Type
Polyclonal Antibody
Gene ID
5093
Swiss Prot
Q15365
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:100
Calculated MW37kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human PCBP1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymPCBP1;HNRPE1;HNRPX;hnRNP-E1;hnRNP-X ;
Images
  • A1044: image 1

    Western blot analysis of extracts of various cell lines, using PCBP1 antibody.

  • A1044: image 2

    Immunohistochemistry of paraffin-embedded human stomach using PCBP1 antibody at dilution of 1:100 (40x lens).

Background

hnRNP E1 is a member of the hnRNP family of proteins that are involved in pre-mRNA processing and mRNA export, localization, stability, and translation (1-6). hnRNP E1 exerts a wide range of biological functions, such as transcriptional activation of mouse MOR gene expression (7), attenuation of alternative splicing of GHR pseudoexon expression (8), stabilization of collagen I and II (9), beta-globin (10), and androgen receptor (11) mRNAs, and regulation of translation of various genes including Dab2, ILEI, and Bag-1 (12,13). hnRNP E1 is ubiquitously expressed. Phosphorylation of hnRNP E1 affects its RNA binding affinity (13,14).

Protocol

N/A

MSDS
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