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Reactivity | Human Mouse |
Tested applications | WB IF |
Recommended Dilution | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
Calculated MW | 39kDa |
Observed MW | Refer to figures |
Immunogen | Recombinant protein of human PCGF6 |
Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | MBLR; RNF134; |
The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified.
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