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sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse |
| Tested applications | WB IHC IP |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:20 - 1:200 IP 1:20 - 1:50 |
| Calculated MW | 61kDa |
| Observed MW | Refer to figures |
| Immunogen | A synthetic Peptide of human PDE1A |
| Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | HCAM1; HCAM-1; HSPDE1A; CAM-PDE-1A; |
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001
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