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Reactivity | Human Mouse Rat |
Tested applications | WB IP |
Recommended Dilution | WB 1:500 - 1:2000 IP 1:20 - 1:50 |
Calculated MW | 81kDa |
Observed MW | Refer to figures |
Immunogen | A synthetic Peptide of human PDE1C |
Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | Hcam3; hCam-3; cam-PDE 1C; |
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992
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